THE SINGLE LATE TC-99(M) GRANULOCYTE ANTIBODY SCAN IN INFLAMMATORY DISEASES

被引：33

作者：

BECKER, WS

SAPTOGINO, A

WOLF, FG

机构：

[1] Department of Nuclear Medicine of the Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, 8520

来源：

NUCLEAR MEDICINE COMMUNICATIONS | 1992年 / 13卷 / 03期

关键词：

D O I：

10.1097/00006231-199203000-00009

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Immunoscintigraphy using 555-740 MBq Tc-99(m)-labelled monoclonal antigranulocyte antibodies (IgG1 against NCA-95) (BW250/183) was performed in 56 patients. In 32 of them inflammatory or infectious lesions were proven or excluded histologically. Gamma camera scans were performed 4 to 6 and 20 h postinjection (p.i.). Eight of 14 infectious or inflammatory lesions could be detected in the early scan (4-6 h p.i.). Sensitivity, specificity and diagnostic accuracy of the early scan were 57, 89 and 75%. sensitivity, specificity and diagnostic accuracy in 19 patients with bone or prosthetic bone infections (87, 81 and 84%, respectively) were lower than in patients with abdominal or soft tissue infections (100%). The overall sensitivity, specificity and diagnostic accuracy of the 20 h scan was 86, 89 and 88%, respectively. It is concluded that the high diagnostic accuracy of immunoscintigraphy justifies a broader application of the scan in the diagnosis of infectious diseases. It is recommended that only late scans (20 h p.i.) are necessary.

引用

页码：186 / 192

页数：7

共 24 条

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