MODEL INVOLVING GENE INACTIVATION IN THE GENERATION OF AUTOSOMAL RECESSIVE MUTANTS IN MAMMALIAN-CELLS IN CULTURE

被引：42

作者：

SIMON, AE

TAYLOR, MW

BRADLEY, WEC

THOMPSON, LH

机构：

[1] UNIV CALIF LAWRENCE LIVERMORE NATL LAB,DIV BIOMED SCI,LIVERMORE,CA 94550

[2] CTR HOSP NOTRE DAME,INST CANC MONTREAL,MONTREAL H2L 4M1,QUEBEC,CANADA

来源：

MOLECULAR AND CELLULAR BIOLOGY | 1982年 / 2卷 / 09期

关键词：

D O I：

10.1128/MCB.2.9.1126

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1126 / 1133

页数：8

共 24 条

[1] MUTAGENICITY TESTING IN MAMMALIAN-CELLS .1. DERIVATION OF A CHINESE-HAMSTER OVARY CELL-LINE HETEROZYGOUS FOR THE ADENINE PHOSPHORIBOSYLTRANSFERASE AND THYMIDINE KINASE LOCI [J].

ADAIR, GM ;

CARVER, JH ;

WANDRES, DL .

MUTATION RESEARCH, 1980, 72 (02) :187-205

[2]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[3] REVERSIBLE INACTIVATION OF AUTOSOMAL ALLELES IN CHINESE-HAMSTER CELLS [J].

BRADLEY, WEC .

JOURNAL OF CELLULAR PHYSIOLOGY, 1979, 101 (02) :325-340

[4] HIGH-FREQUENCY NONRANDOM MUTATIONAL EVENT AT THE ADENINE PHOSPHORIBOSYLTRANSFERASE (APRT) LOCUS OF SIB-SELECTED CHO VARIANTS HETEROZYGOUS FOR APRT [J].

BRADLEY, WEC ;

LETOVANEC, D .

SOMATIC CELL GENETICS, 1982, 8 (01) :51-66

[5] SEGREGATION OF RECESSIVE PHENOTYPES IN SOMATIC-CELL HYBRIDS - ROLE OF MITOTIC RECOMBINATION, GENE INACTIVATION, AND CHROMOSOME NONDISJUNCTION [J].

CAMPBELL, CE ;

WORTON, RG .

MOLECULAR AND CELLULAR BIOLOGY, 1981, 1 (04) :336-346

[6] MUTATIONS AFFECTING ADENINE PHOSPHORIBOSYL TRANSFERASE-ACTIVITY IN CHINESE-HAMSTER CELLS [J].

CHASIN, LA .

CELL, 1974, 2 (01) :37-41

[7] ALTERATION IN STRUCTURE OF MULTIFUNCTIONAL PROTEIN FROM CHINESE-HAMSTER OVARY CELLS DEFECTIVE IN PYRIMIDINE BIOSYNTHESIS .4 [J].

DAVIDSON, JN ;

PATTERSON, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1979, 76 (04) :1731-1735

[8] GENETIC AND BIOCHEMICAL STUDIES WITH ADENOSINE-ANALOGS TOYOCAMYCIN AND TUBERCIDIN - MUTATION AT ADENOSINE KINASE LOCUS IN CHINESE-HAMSTER CELLS [J].

GUPTA, RS ;

SIMINOVITCH, L .

SOMATIC CELL GENETICS, 1978, 4 (06) :715-735

[9] PURIFICATION OF ADENINE PHOSPHORIBOSYLTRANSFERASE BY AFFINITY CHROMATOGRAPHY [J].

HERSHEY, HV ;

TAYLOR, MW .

PREPARATIVE BIOCHEMISTRY, 1978, 8 (06) :453-462

[10] MUTANTS OF CULTURED CHINESE-HAMSTER CELLS DEFICIENT IN ADENINE PHOSPHORIBOSYL TRANSFERASE [J].

JONES, GE ;

SARGENT, PA .

CELL, 1974, 2 (01) :43-54

← 1 2 3 →