IMMUNE-RESPONSE TO TREPONEMA-PERTENUE AND TREPONEMA-PALLIDUM NICHOLS IN PATIENTS WITH YAWS

被引：8

作者：

MARTIN, PMV

COCKAYNE, A

GEORGES, AJ

PENN, CW

机构：

[1] UNIV NOTTINGHAM,DEPT MICROBIOL,NOTTINGHAM NG7 2UH,ENGLAND

[2] UNIV BIRMINGHAM,SCH BIOL SCI,BIRMINGHAM B15 2TT,W MIDLANDS,ENGLAND

来源：

RESEARCH IN MICROBIOLOGY | 1990年 / 141卷 / 02期

关键词：

Immune Response; Africa; Syphilis; Motscles: Treponema pallidum; Treponema pertenue; Pian; Résponse immunitaire; Afrique; Treponema pallidum; Yaws;

D O I：

10.1016/0923-2508(90)90027-N

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Human sera from African patients with acute yaws were analysed by Western blot (WB) against antigens of Treponema pallidum Nichols and two Treponema pertenue isolates. The Western blot patterns were remarkably similar from one patient to another, and strains of both subspecies exhibited exactly the same banding pattern. Sera from yaws patients failed to detect at least one antigen in T. pertenue which was absent from T. pallidum. © 1990.

引用

收藏

页码：181 / 186

页数：6

相关论文

共 22 条

[1] MOLECULAR-BASIS OF IMMUNOLOGICAL CROSS-REACTIVITY BETWEEN TREPONEMA-PALLIDUM AND TREPONEMA-PERTENUE [J].

BAKERZANDER, SA ;

LUKEHART, SA .

INFECTION AND IMMUNITY, 1983, 42 (02) :634-638

[2]

BAUDON D, 1984, ANN SOC BELG MED TR, V34, P397

[3]

CIRERA P, 1977, B SOC PATHOL EXOT, V70, P32

[4] SODIUM DODECYL SULFATE-POLYACRYLAMIDE GEL-ELECTROPHORESIS IMMUNOBLOTTING AS A SEROLOGICAL TOOL IN THE DIAGNOSIS OF SYPHILITIC INFECTIONS [J].

HENSEL, U ;

WELLENSIEK, HJ ;

BHAKDI, S .

JOURNAL OF CLINICAL MICROBIOLOGY, 1985, 21 (01) :82-87

[5]

HUDSON EH, 1964, BRIT J VENER DIS, V40, P43

[6] IMMUNOLOGICAL RELATIONSHIPS AMONG SPECIES AND STRAINS OF VIRULENT TREPONEMES AS DETERMINED WITH THE TREPONEMAL IMMOBILIZATION TEST [J].

KHAN, AS ;

NELSON, RA ;

TURNER, TB .

AMERICAN JOURNAL OF HYGIENE, 1951, 53 (03) :296-316

[7] CLEAVAGE OF STRUCTURAL PROTEINS DURING ASSEMBLY OF HEAD OF BACTERIOPHAGE-T4 [J].

LAEMMLI, UK .

NATURE, 1970, 227 (5259) :680-+

[8] MOLECULAR SPECIFICITIES OF MONOCLONAL-ANTIBODIES DIRECTED AGAINST VIRULENT TREPONEMA-PALLIDUM [J].

MARCHITTO, KS ;

SELLANDGROSSLING, CK ;

NORGARD, MV .

INFECTION AND IMMUNITY, 1986, 51 (01) :168-176

[9] CLINICAL ASPECTS AND USEFULNESS OF INDIRECT ABSORBED IMMUNOFLUORESCENCE FOR DIAGNOSIS OF YAWS IN CENTRAL-AFRICA [J].

MARTIN, PMV ;

GONZALEZ, JP ;

MARTIN, MH ;

GEORGESCOURBOT, MC ;

PALISSON, MJ ;

GEORGES, AJ .

JOURNAL OF CLINICAL MICROBIOLOGY, 1988, 26 (11) :2432-2433

[10] GENETIC-RELATIONSHIP BETWEEN TREPONEMA-PALLIDUM AND TREPONEMA-PERTENUE, 2 NON-CULTIVABLE HUMAN PATHOGENS [J].

MIAO, RM ;

FIELDSTEEL, AH .

JOURNAL OF BACTERIOLOGY, 1980, 141 (01) :427-429