APPLICATION OF THERMOSPRAY LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY FOR THE ANALYSIS OF CHLORAMPHENICOL AND 3 RELATED-COMPOUNDS

被引：8

作者：

KORFMACHER, WA ^{[1
]}

GETEK, TA ^{[1
]}

HANSEN, EB ^{[1
]}

CERNIGLIA, CE ^{[1
]}

ABOUKHALIL, S ^{[1
]}

YUNIS, AA ^{[1
]}

机构：

[1] UNIV MIAMI,SCH MED,DEPT MED,MIAMI,FL 33101

来源：

JOURNAL OF CHROMATOGRAPHIC SCIENCE | 1990年 / 28卷 / 05期

关键词：

D O I：

10.1093/chromsci/28.5.236

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The thermospray (TS) liquid chromatographic-mass spectrometric analysis of the antibiotic chloramphenicol and three related compounds is presented. The three additional compounds are dehydrochloramphenicol, aminodehydrochloramphenicol, and nitrophenylaminopropanediol. Baseline separation of the four compounds is achieved. The TS mass spectrum of each of the four compounds includes a prominent [MH]+ ion plus some fragment ion peaks.

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页码：236 / 238

页数：3

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