EFFICIENT SYNTHESIS OF 3-SUBSTITUTED LACTAMS USING MEERWEIN ESCHENMOSER CLAISEN [3,3] SIGMATROPIC REARRANGEMENTS

被引：10

作者：

COATES, B ^{[1
]}

MONTGOMERY, D ^{[1
]}

STEVENSON, PJ ^{[1
]}

机构：

[1] QUEENS UNIV BELFAST,SCH CHEM,BELFAST BT9 5AG,ANTRIM,NORTH IRELAND

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 33期

关键词：

3,3] SIGMATROPIC REARRANGEMENT; 3-SUBSTITUTED LACTAMS; QUARTERNARY CHIRAL CENTERS;

D O I：

10.1016/S0040-4039(00)79904-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3-Allyl substituted five, six, and seven membered ring lactams are readily available in good yields and reasonable selectivity by a formal Meerwein Eschenmoser Claisen [3,3] rearrangement, using the readily available N,N-dialkylalkoxymethylene iminium salts and lithium alkoxides derived from allyl alcohols.

引用

页码：4199 / 4202

页数：4

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