CIRCADIAN-RHYTHMS IN 6-SULPHATOXYMELATONIN AND NOCTURNAL SLEEP IN BLIND-CHILDREN

被引：43

作者：

TZISCHINSKY, O ^{[1
]}

SKENE, D ^{[1
]}

EPSTEIN, R ^{[1
]}

LAVIE, P ^{[1
]}

机构：

[1] TECHNION ISRAEL INST TECHNOL,FAC MED,SLEEP LAB,IL-32000 HAIFA,ISRAEL

来源：

CHRONOBIOLOGY INTERNATIONAL | 1991年 / 8卷 / 03期

关键词：

6-SULPHATOXYMELATONIN; BLIND; CIRCADIAN RHYTHMS; ACTIGRAPH;

D O I：

10.3109/07420529109063923

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This article describes the relationship between melatonin secretion and sleep quality and subjective complaints about sleep in totally blind children. Eleven boarding-school children (mean age 15.2 years) participated. The major urinary melatonin metabolite 6-sulphatoxymelatonin (aMT6s) was measured five times a day for 48 h. Sleep-wake cycles were recorded by continuous actigraphic recordings during the same time period. Results showed that delayed secretory peaks in aMT6s were significantly associated with disturbed nocturnal sleep and with complaints about morning fatigue.

引用

页码：168 / 175

页数：8

共 19 条

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