INVESTIGATIONS OF THE INFLUENCE OF SILANOL GROUPS ON THE SEPARATION OF ENANTIOMERS BY LIQUID AND SUPERCRITICAL FLUID CHROMATOGRAPHY

被引：14

作者：

BRUGGER, R ^{[1
]}

ARM, H ^{[1
]}

机构：

[1] UNIV BERN,INST ORGAN CHEM,FREIESTR 3,CH-3012 BERN,SWITZERLAND

来源：

JOURNAL OF CHROMATOGRAPHY | 1992年 / 592卷 / 1-2期

关键词：

D O I：

10.1016/0021-9673(92)85101-X

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Chiral stationary phases based on (R)-N-(1-phenylethyl)-N'-(propylsilyl)urea covalently bonded to silica at different coverage densities with or without end-capped silanol groups were tested by liquid and supercritical fluid chromatography. Greater enantioselectivities and in most instances unexpectedly greater retentions were observed with the end-capped phases. This indicates that silanol groups may influence the interactions between the analyte and a chiral stationary phase.

引用

页码：309 / 316

页数：8

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