A THIN-FILM MICROELECTRODE ARRAY FOR MONITORING EXTRACELLULAR NEURONAL-ACTIVITY IN-VITRO

被引：71

作者：

NISCH, W

BOCK, J

EGERT, U

HAMMERLE, H

MOHR, A

机构：

[1] Naturwissenschaftliches und Medizinisches Institut an der Universitat Tubingen in Reutlingen, 72762 Reutlingen

来源：

BIOSENSORS & BIOELECTRONICS | 1994年 / 9卷 / 9-10期

关键词：

BIOELECTRONIC; MICROELECTRODE-ARRAY; SPATIAL SENSITIVITY; ACTION POTENTIAL; SIMULATION; IMPEDANCE;

D O I：

10.1016/0956-5663(94)80072-3

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A planar array of microelectrodes has been developed for monitoring a the electrical activity of neurons in cell culture. The microelectrode array was tested and characterized using impedance measurements and SEM. To verify the spatial sensitivity of the microelectrodes we used a specially developed simulation device.

引用

页码：737 / 741

页数：5

共 13 条

[1] AMATNIEK E, 1957, IRE T MED ELECTRON, P3
[2] AN EXTRACELLULAR MICROELECTRODE ARRAY FOR MONITORING ELECTROGENIC CELLS IN CULTURE
CONNOLLY, P
CLARK, P
CURTIS, ASG
DOW, JAT
WILKINSON, CDW
[J]. BIOSENSORS & BIOELECTRONICS, 1990, 5 (03) : 223 - 234
[3] PERFORMANCE OF PLANAR MULTISITE MICROPROBES IN RECORDING EXTRACELLULAR SINGLE-UNIT INTRACORTICAL ACTIVITY
DRAKE, KL
WISE, KD
FARRAYE, J
ANDERSON, DJ
BEMENT, SL
[J]. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1988, 35 (09) : 719 - 732
[4] GESTELAND RC, 1959, P IRE, P1856
[5] SIMULTANEOUS SINGLE UNIT RECORDING INVITRO WITH A PHOTOETCHED LASER DEINSULATED GOLD MULTI-MICRO-ELECTRODE SURFACE
GROSS, GW
[J]. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1979, 26 (05) : 273 - 279
[6] HAMMERLE H, 1994, IN PRESS BIOSENSORS
[7] NASTUK WL, 1964, PHYSICAL TECHNIQUES, V5
[8] PICKARD S, 1989, BIOSENS BIOELECTRON, P303
[9] PINE J, 1987, P573
[10] ELECTRICAL PROPERTIES OF METAL MICROELECTRODES
ROBINSON, DA
[J]. PROCEEDINGS OF THE INSTITUTE OF ELECTRICAL AND ELECTRONICS ENGINEERS, 1968, 56 (06): : 1065 - &

← 1 2 →