PROTEIN KINASE-C SUBTYPES IN TISSUES DERIVED FROM NEURAL CREST

被引：9

作者：

KODA, Y ^{[1
]}

KOBAYASHI, H ^{[1
]}

MIZUKI, T ^{[1
]}

OKAZAKI, M ^{[1
]}

UEZONO, Y ^{[1
]}

YANAGIHARA, N ^{[1
]}

WADA, A ^{[1
]}

IZUMI, F ^{[1
]}

机构：

[1] UNIV OCCUPAT & ENVIRONM HLTH,SCH MED,DEPT PHARMACOL,1-1 ISEIGAOKA,YAHATANISHI KU,KITAKYUSHU,FUKUOKA 807,JAPAN

来源：

BRAIN RESEARCH | 1990年 / 518卷 / 1-2期

关键词：

Catecholamine; Neural crest; Protein kinase C; Subtype;

D O I：

10.1016/0006-8993(90)90993-L

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Subtypes of protein kinase C were determined in tissues derived from neural crest. The bovine adrenal medulla and rat superior cervical ganglia contained type III enzyme as the major subtype with a small amount of type II enzyme. In PC12 cells, treated with or without nerve growth factor, type III was the major subtype but a minor peak which is distinct from types II and III was observed. These results show that the type III enzyme is prevalent in various differentiation stages of neural crest and suggest that the enzyme relevant to the regulation of catecholamine synthesis and release in these cells is type III. © 1990.

引用

页码：334 / 336

页数：3

共 18 条

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