DETECTION OF NONVOLATILE SPECIES BY LASER DESORPTION ATMOSPHERIC-PRESSURE MASS-SPECTROMETRY

被引：30

作者：

KOLAITIS, L ^{[1
]}

LUBMAN, DM ^{[1
]}

机构：

[1] UNIV MICHIGAN,DEPT CHEM,ANN ARBOR,MI 48109

来源：

ANALYTICAL CHEMISTRY | 1986年 / 58卷 / 11期

关键词：

AMINO ACIDS - Spectroscopic Analysis - DRUG PRODUCTS - Spectroscopic Analysis - SPECTROSCOPY - Laser Applications;

D O I：

10.1021/ac00124a007

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

This work examines the use of laser desorption as a means of volatilizing thermally labile compounds for detection in atmospheric pressure mass spectrometry. A number of different classes of compounds have been examined including amino acids, purine and pyrimidine bases and their nucleosides, drugs, vitamins, and catecholamines. The main advantage of this method is that desorption of neutrals and the atmospheric pressure ionization process are performed in two separate steps as compared to LDMS where desorption and ionization occurs in one step.

引用

页码：2137 / 2142

页数：6

共 30 条

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[2]

BARBER M, 1980, SOFT IONIZATION BIOL

[3]

Beckey HD, 1969, INT J MASS SPECTROM, V2, P500

[4] SECONDARY ION EMISSION FROM MIXTURES OF STIMULANTS, BARBITURATES, OPIATES AND AMINO-ACIDS [J].