COMPARATIVE-STUDY OF THE FERMENTATIVE CHARACTERISTICS OF INULIN AND DIFFERENT TYPES OF FIBER IN RATS INOCULATED WITH A HUMAN WHOLE FECAL FLORA

被引：54

作者：

ROLAND, N

NUGONBAUDON, L

ANDRIEUX, C

SZYLIT, O

机构：

[1] Institut nationale de la Recherche Agronomique, Unité d'Ecolozie et Physiologie du Svsteme Digestif, Cedex, Jouy-en-Josas

来源：

BRITISH JOURNAL OF NUTRITION | 1995年 / 74卷 / 02期

关键词：

DIETARY FIBER; FERMENTATION; GNOTOBIOTIC RATS;

D O I：

10.1079/BJN19950127

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

It is known that the physico-chemical characteristics of fibre modify their fermentation characteristics in the colon, Previously we showed the varying effects of inulin and different types of fibre on the hepatic and intestinal xenobiotic-metabolizing enzymes (XME) in initially germ-free rats inoculated with a human, methanogenic, whole-faecal flora (Roland et al, 1994), The aim of the present work was to assess whether or not these effects could be related to differences in production of fermentation metabolites (gases excreted is vivo acid caecal metabolites) due to the different compositions of fibre, The different types of fibres were analysed with regard to their solubility and their composition of neutral monomers and uronic acids, Inulin was totally soluble, carrot (Daucus carota), cocoa (Theobroma cacao) and wheat bran were partially soluble;pea (Pisum sativum) and oat were nearly totally insoluble, Uronic acids were found mostly in carrot and cocoa fibre, Glucose was present as the main neutral monomer in each fibre type, Xylose was found also in wheat bran, pea and oat fibres, and arabinose was found in wheat bran, Inulin consumption led to high levels of H-2 production but no CH4 production, to a 4-fold greater caecal concentration of butyrate than with the other fibres and to a decrease in caecal pH. Conversely, rats fed on carrot or cocoa fibre produced a large amount of CH4 but no H-2 and generated a different profile of short-chain fatty acids (SCFA), The lowest amounts of gases and SCFA were found in rats fed on wheat bran, pea and oat fibre, We observed a relationship between the caecal concentration of SCFA and the activity of hepatic glutathione-S-transferase (EC 2.5.1.18) but no direct link was shown between the other XME and the fermentation profile.

引用

页码：239 / 249

页数：11

共 31 条

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