THE NUCLEOTIDE-SEQUENCE OF A CPG ISLAND DEMONSTRATES THE PRESENCE OF THE 1ST-EXON OF THE GENE ENCODING THE HUMAN LYSOSOMAL MEMBRANE-PROTEIN LAMP-2 AND ASSIGNS THE GENE TO XQ24

被引：16

作者：

MANONI, M ^{[1
]}

TRIBIOLI, C ^{[1
]}

LAZZARI, B ^{[1
]}

DEBELLIS, G ^{[1
]}

PATROSSO, C ^{[1
]}

PERGOLIZZI, R ^{[1
]}

PELLEGRINI, M ^{[1
]}

MAESTRINI, E ^{[1
]}

RIVELLA, S ^{[1
]}

VEZZONI, P ^{[1
]}

TONIOLO, D ^{[1
]}

机构：

[1] CNR, IST GENET BIOCHIM & EVOLUZ, I-27100 PAVIA, ITALY

来源：

GENOMICS | 1991年 / 9卷 / 03期

关键词：

D O I：

10.1016/0888-7543(91)90424-D

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

An EagI-EcoRI clone of human genomic DNA, p2-7, mapped to Xq24 has been sequenced. This analysis has confirmed the presence of a CpG island and has identified the first exon of the human LAMP2 gene, encoding a glycoprotein of the lysosomal membrane. Since the p2-7 clone corresponds to single-copy DNA, we can assign the human LAMP2 gene to Xq24. © 1991.

引用

页码：551 / 554

页数：4

共 15 条

[1] CPG ISLANDS OF THE X-CHROMOSOME ARE GENE ASSOCIATED [J].