CYCLOSPORINE-ASSOCIATED CENTRAL NERVOUS-SYSTEM TOXICITY AFTER ALLOGENEIC BONE-MARROW TRANSPLANTATION

被引：156

作者：

ATKINSON, K ^{[1
]}

BIGGS, J ^{[1
]}

DARVENIZA, P ^{[1
]}

BOLAND, J ^{[1
]}

CONCANNON, A ^{[1
]}

DODDS, A ^{[1
]}

机构：

[1] ST VINCENTS HOSP, DEPT NEUROL, SYDNEY, NSW 2010, AUSTRALIA

来源：

TRANSPLANTATION | 1984年 / 38卷 / 01期

关键词：

D O I：

10.1097/00007890-198407000-00009

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Five of 64 [human] recipients of HLA-identical sibling marrow allografts who were given cyclosporine (CSP) to minimize graft-vs.-host disease posttransplant had a serious neurological illness thought to be due to CSP. Characteristic clinical features included a motor spinal cord syndrome, a cerebellar-like syndrome and mental confusion. All 5 recovered when the CSP dose was reduced or the drug was stopped.

引用

页码：34 / 37

页数：4

共 22 条

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