MAGNETIC-FIELDS ASSOCIATED WITH SPREADING DEPRESSION IN ANESTHETIZED RABBITS

被引：38

作者：

GARDNERMEDWIN, AR

TEPLEY, N

BARKLEY, GL

MORAN, J

NAGELLEIBY, S

SIMKINS, RT

WELCH, KMA

机构：

[1] HENRY FORD HOSP,DEPT NEUROL,DETROIT,MI 48202

[2] OAKLAND UNIV,DEPT PHYS,ROCHESTER,MI 48309

来源：

BRAIN RESEARCH | 1991年 / 540卷 / 1-2期

关键词：

SPREADING DEPRESSION; MIGRAINE; MAGNETIC RECORDING; MAGNETOENCEPHALOGRAPHY; SQUID;

D O I：

10.1016/0006-8993(91)90502-M

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Magnetic fields were measured with SQUID magnetometry outside the skull of anaesthetised rabbits during initiation and propagation of spreading depression (SD) in the cortex. Slowly changing fields (up to 1.4 pT) were observed during the propagation phase, from 4-8.5 min after initiation of SD with KCI application, with maxima at about 6 min. The peak amplitude of the equivalent net dipole generators in the brain was ca. 28-mu-A.mm, substantially less than previously observed with SD in vitro, but large enough that similar signals might be detectable in man.

引用

页码：153 / 158

页数：6

共 11 条

[1]

BARKLEY GL, 1989, J PHYSIOL-LONDON, V418, pP101

[2]

BURES J, 1974, MECHANISM APPLICATIO

[3]

GARDNERMEDWIN AR, 1981, J EXP BIOL, V95, P111

[4]

GARDNERMEDWIN AR, 1990, ADV BIOMAGNETISM, P323