EFFECT OF GENDER ON GLUCOSE-UTILIZATION RATES IN HEALTHY HUMANS - A POSITRON EMISSION TOMOGRAPHY STUDY

被引：48

作者：

MIURA, SA ^{[1
]}

SCHAPIRO, MB ^{[1
]}

GRADY, CL ^{[1
]}

KUMAR, A ^{[1
]}

SALERNO, JA ^{[1
]}

KOZACHUK, WE ^{[1
]}

WAGNER, E ^{[1
]}

RAPOPORT, SI ^{[1
]}

HORWITZ, B ^{[1
]}

机构：

[1] NIA,NEUROSCI LAB,BLDG 10,RM 6C-414,BETHESDA,MD 20892

来源：

JOURNAL OF NEUROSCIENCE RESEARCH | 1990年 / 27卷 / 04期

关键词：

POSITRON EMISSION TOMOGRAPHY; DEOXY-GLUCOSE; BRAIN; SEX DIFFERENCES; BRAIN METABOLISM;

D O I：

10.1002/jnr.490270410

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Positron emission tomography (PET) was used with 18fluorodeoxyglucose to see if gender differences in resting cerebral glucose utilization could be detected. Thirty-two healthy subjects (15 women and 17 men; age range: 21-38 yr) were examined using a high-resolution PET scanner to determine the regional cerebral metabolic rate for glucose (CMRglc) in 65 gray matter regions of interest. Whole brain CMRglc did not differ significantly between the two genders, nor did any of the regional CMRglc values. Only 1 of 65 ratios of regional-to-whole brain CMRglc differed significantly between men and women, which is consistent with chance. These results indicate that there are no differences in resting regional cerebral glucose utilization between young men and women.

引用

页码：500 / 504

页数：5

共 29 条

[1] BARON JC, 1985, POSITRON EMISSION TO, P203
[2] CEREBRAL GLUCOSE METABOLIC RATES IN NORMAL HUMAN FEMALES VERSUS NORMAL MALES
BAXTER, LR
MAZZIOTTA, JC
PHELPS, ME
SELIN, CE
GUZE, BH
FAIRBANKS, L
[J]. PSYCHIATRY RESEARCH, 1987, 21 (03) : 237 - 245
[3] BROOKS RA, 1982, J NUCL MED, V23, P538
[4] SEX-DIFFERENCES IN COGNITIVE-FUNCTIONING - EVIDENCE, DETERMINANTS, IMPLICATIONS
BURSTEIN, B
BANK, L
JARVIK, LF
[J]. HUMAN DEVELOPMENT, 1980, 23 (05) : 289 - 313
[5] BUTLER S, 1984, PROG BRAIN RES, V61, P443
[6] COMPUTER-ASSISTED CATEGORIZATION OF BRAIN COMPUTERIZED-TOMOGRAPHY PIXELS INTO CEREBROSPINAL-FLUID, WHITE MATTER, AND GRAY-MATTER
DELEO, JM
SCHWARTZ, M
CREASEY, H
CUTLER, N
RAPOPORT, SI
[J]. COMPUTERS AND BIOMEDICAL RESEARCH, 1985, 18 (01): : 79 - 88
[7] DEVOUS ME, 1986, J CEREB BLOOD FLOW M, V3, P95
[8] MORPHOLOGIC CEREBRAL CORTICAL ASYMMETRY IN MALE AND FEMALE RATS
DIAMOND, MC
DOWLING, GA
JOHNSON, RE
[J]. EXPERIMENTAL NEUROLOGY, 1981, 71 (02) : 261 - 268
[9] HUMAN-BRAIN GLUCOSE-UTILIZATION AND COGNITIVE FUNCTION IN RELATION TO AGE
DUARA, R
GRADY, C
HAXBY, J
INGVAR, D
SOKOLOFF, L
MARGOLIN, RA
MANNING, RG
CUTLER, NR
RAPOPORT, SI
[J]. ANNALS OF NEUROLOGY, 1984, 16 (06) : 702 - 713
[10] Eycleshymer AC, 1911, CROSS SECTION ANATOM

← 1 2 3 →