SYNTHESIS OF SOME SEMISYNTHETIC NEMADECTINS

被引：6

作者：

MOWBRAY, CE ^{[1
]}

RAMSAY, MVJ ^{[1
]}

ROBERTS, SM ^{[1
]}

机构：

[1] GLAXO GRP RES LTD,DEPT MICROBIOL CHEM,GREENFORD UB6 0HE,MIDDX,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 06期

关键词：

D O I：

10.1039/p19900001813

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The natural product (3) has been modified to provide the semi-synthetic nemadectins (15), (17), and (18).

引用

页码：1813 / 1819

页数：7

共 11 条

[1] AVERMECTINS - STRUCTURE DETERMINATION [J].

ALBERSSCHONBERG, G ;

ARISON, BH ;

CHABALA, JC ;

DOUGLAS, AW ;

ESKOLA, P ;

FISHER, MH ;

LUSI, A ;

MROZIK, H ;

SMITH, JL ;

TOLMAN, RL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (14) :4216-4221

[2] CHEMICAL-TRANSFORMATIONS OF S541 FACTORS (A)-(D) - PREPARATION AND REACTIONS OF THE 23-KETONES [J].

BEDDALL, NE ;

HOWES, PD ;

RAMSAY, MVJ ;

ROBERTS, SM ;

SLAWIN, AMZ ;

SUTHERLAND, DR ;

TILEY, EP ;

WILLIAMS, DJ .

TETRAHEDRON LETTERS, 1988, 29 (21) :2595-2598

[3]

CARTER GT, 1987, J CHEM SOC CHEM COMM, P956

[4] AVERMECTINS AND MILBEMYCINS [J].

DAVIES, HG ;

GREEN, RH .

NATURAL PRODUCT REPORTS, 1986, 3 (02) :87-121

[5]

Fisher M.H., 1984, MACROLIDE ANTIBIOTIC, P553

[6] PROGRESS IN NATURAL PRODUCT CHEMISTRY BY THE CHIRON AND RELATED APPROACHES - SYNTHESIS OF AVERMECTIN-B1A [J].

HANESSIAN, S ;

UGOLINI, A ;

HODGES, PJ ;

BEAULIEU, P ;

DUBE, D ;

ANDRE, C .

PURE AND APPLIED CHEMISTRY, 1987, 59 (03) :299-316

[7] NOVEL ANTIPARASITIC AGENTS DERIVED BY MODIFICATION OF A NEW NATURAL PRODUCT SERIES [J].

RAMSAY, MVJ ;

ROBERTS, SM ;

RUSSELL, JC ;

SHINGLER, AH ;

SLAWIN, AMZ ;

SUTHERLAND, DR ;

TILEY, EP ;

WILLIAMS, DJ .

TETRAHEDRON LETTERS, 1987, 28 (44) :5353-5356

[8] MILBEMYCIN AVERMECTIN STUDIES .5. TOTAL SYNTHESIS OF MILBEMYCIN -BETA-3 AND ITS C(12) EPIMER [J].

SCHOW, SR ;

BLOOM, JD ;

THOMPSON, AS ;

WINZENBERG, KN ;

SMITH, AB .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (10) :2662-2674

[9] N-BROMOACETAMIDE AS A SELECTIVE REAGENT FOR THE FUNCTIONALIZATION OF THE 10,11 DOUBLE-BOND OF AVERMECTIN B1A [J].

SHIH, TL ;

MROZIK, H ;

RUIZSANCHEZ, J ;

FISHER, MH .

JOURNAL OF ORGANIC CHEMISTRY, 1989, 54 (06) :1459-1463

[10] BIOSYNTHETIC ORIGIN OF THE CARBON SKELETON AND OXYGEN-ATOMS OF THE LL-F28249-ALPHA - A POTENT ANTIPARASITIC MACROLIDE [J].

TSOU, HR ;

AHMED, ZH ;

FIALA, RR ;

BULLOCK, MW ;

CARTER, GT ;

GOODMAN, JJ ;

BORDERS, DB .

JOURNAL OF ANTIBIOTICS, 1989, 42 (03) :398-406

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