INHIBITION OF HUGGINS TUMORS BY FORCED RESTRAINT

被引：30

作者：

NEWBERRY, BH ^{[1
]}

GILDOW, J ^{[1
]}

WOGAN, J ^{[1
]}

REESE, RL ^{[1
]}

机构：

[1] KENT STATE UNIV, DEPT PSYCHOL, KENT, OH 44242 USA

来源：

PSYCHOSOMATIC MEDICINE | 1976年 / 38卷 / 03期

关键词：

D O I：

10.1097/00006842-197605000-00001

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Chronically administered restraint inhibits the development of DMBA [7,12-dimethybenz(a)anthracene]-induced rat mammary tumors. The effect is exhibited in a lower proportion of positive responses, increased latency of tumor development, and lower number of tumors in positive animals when restrained animals are compared with controls. Organ weights failed to show a stress response to restraint. Molar activity data from the 3rd experiment indicated that early in the experiment activity increased among the restrained animals on release from restraint. A 4th experiment, which employed a crystal accelerometer to assess activity, produced a similar activity pattern and also provided evidence of adrenal ascorbic acid depletion as a function of restraint.

引用

页码：155 / 162

页数：8

共 27 条

[1]

AMKRAUT A, 1972, CANCER RES, V32, P1428

[2] EFFECT OF ADRENALECTOMY ON GROWTH OF MAMMARY TUMOURS INDUCED BY 3-METHYLCHOLANTHRENE IN RATS [J].