ASSIGNMENT OF 2 HUMAN ALPHA-1,3-GALACTOSYLTRANSFERASE GENE-SEQUENCES (GGTA1 AND GGTA1P) TO CHROMOSOME-9Q33-Q34 AND CHROMOSOME-12Q14-Q15

α-1,3-Galactosyltransferase is a terminal glycosyltransferase that is widely expressed in a variety of mammalian species, with the notable exception of man, apes, and Old World monkeys. Although transcripts for this enzyme are not detectable in humans, homologous sequences have been identified in human genomic DNA. These sequences correspond to a processed pseudogene that maps to chromosome 12 and the inactivated remnant of the once functional source gene that maps to chromosome 9. We have now established that the former sequence (GGTA1) is localized to 12q14-q15 and the latter sequence (GGTA1P) is localized to 9q33-q34. © 1992.