OCCURRENCE OF THE REGULATORY NUCLEOTIDES PPGPP AND PPPGPP FOLLOWING INDUCTION OF THE STRINGENT RESPONSE IN STAPHYLOCOCCI

被引：57

作者：

CASSELS, R ^{[1
]}

OLIVA, B ^{[1
]}

KNOWLES, D ^{[1
]}

机构：

[1] UNIV LAQUILA, DEPT EXPTL MED, I-67100 LAQUILA, ITALY

来源：

JOURNAL OF BACTERIOLOGY | 1995年 / 177卷 / 17期

关键词：

D O I：

10.1128/jb.177.17.5161-5165.1995

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The stringent response in Escherichia coli and many other organisms is regulated by the nucleotides ppGpp and pppGpp. We show here for the first time that at least six staphylococcal species also synthesize ppGpp and pppGpp upon induction of the stringent response by mupirocin. Spots corresponding to ppGpp and pppGpp on thin-layer chromatograms suggest that pppGpp is the principal regulatory nucleotide synthesized by staphylococci in response to mupirocin, rather than ppGpp as in E. coli.

引用

页码：5161 / 5165

页数：5

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