MODERATE-LEVEL GENE AMPLIFICATION IN METHOTREXATE-RESISTANT CHINESE-HAMSTER OVARY CELLS IS ACCOMPANIED BY CHROMOSOMAL TRANSLOCATIONS AT OR NEAR THE SITE OF THE AMPLIFIED DHFR GENE

被引：53

作者：

FLINTOFF, WF

LIVINGSTON, E

DUFF, C

WORTON, RG

机构：

[1] HOSP SICK CHILDREN,RES INST,TORONTO M5G 1X8,ONTARIO,CANADA

[2] HOSP SICK CHILDREN,DEPT GENET,TORONTO M5G 1X8,ONTARIO,CANADA

[3] UNIV TORONTO,DEPT MED GENET,TORONTO M5G 1X8,ONTARIO,CANADA

来源：

MOLECULAR AND CELLULAR BIOLOGY | 1984年 / 4卷 / 01期

关键词：

D O I：

10.1128/MCB.4.1.69

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：69 / 76

页数：8

共 42 条

[1] ALT FW, 1978, J BIOL CHEM, V253, P1357
[2] CHROMOSOMAL ALTERATIONS ASSOCIATED WITH OVERPRODUCTION OF ASPARAGINE SYNTHETASE IN ALBIZZIIN-RESISTANT CHINESE-HAMSTER OVARY CELLS
ANDRULIS, IL
DUFF, C
EVANSBLACKLER, S
WORTON, R
SIMINOVITCH, L
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1983, 3 (03) : 391 - 398
[3] AMPLIFICATION OF THE METALLOTHIONEIN-I GENE IN CADMIUM-RESISTANT MOUSE CELLS
BEACH, LR
PALMITER, RD
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (04): : 2110 - 2114
[4] BIEDLER JL, 1980, CANCER GENET CYTOGEN, V2, P47, DOI 10.1016/0165-4608(80)90079-5
[5] NOVEL CHROMOSOME ABNORMALITY IN HUMAN NEUROBLASTOMA AND ANTIFOLATE-RESISTANT CHINESE-HAMSTER CELL LINES IN CULTURE
BIEDLER, JL
SPENGLER, BA
[J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1976, 57 (03) : 683 - 695
[6] METAPHASE CHROMOSOME ANOMALY - ASSOCIATION WITH DRUG-RESISTANCE AND CELL-SPECIFIC PRODUCTS
BIEDLER, JL
SPENGLER, BA
[J]. SCIENCE, 1976, 191 (4223) : 185 - 187
[7] GENE AMPLIFICATION IN METHOTREXATE-RESISTANT MOUSE CELLS .2. REARRANGEMENT AND AMPLIFICATION OF NON-DIHYDROFOLATE REDUCTASE GENE-SEQUENCES ACCOMPANY CHROMOSOMAL CHANGES
BOSTOCK, CJ
TYLERSMITH, C
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1981, 153 (02) : 219 - 236
[8] CLONED CDNA SEQUENCES OF THE HYPOXANTHINE GUANINE PHOSPHORIBOSYLTRANSFERASE GENE FROM A MOUSE NEURO-BLASTOMA CELL-LINE FOUND TO HAVE AMPLIFIED GENOMIC SEQUENCES
BRENNAND, J
CHINAULT, AC
KONECKI, DS
MELTON, DW
CASKEY, CT
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (06): : 1950 - 1954
[9] GENE AMPLIFICATION PROCEEDS BY A CHROMOSOME COPY MECHANISM
BROWN, DD
BLACKLER, AW
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1972, 63 (01) : 75 - &
[10] BROWN DD, 1968, SCIENCE, V160, P277

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