THE EFFECTS OF FREEZING OR FREEZE-DRYING ON THE BIOMECHANICAL PROPERTIES OF THE CANINE INTERVERTEBRAL-DISK

被引:14
作者
FLYNN, J [1 ]
RUDERT, MJ [1 ]
OLSON, E [1 ]
BARATZ, M [1 ]
HANLEY, E [1 ]
机构
[1] UNIV PITTSBURGH,DEPT ORTHOPAED SURG,PITTSBURGH,PA 15260
关键词
Biomechanics; Canine; Freeze-drying; Freezing; Intervertebral disc;
D O I
10.1097/00007632-199006000-00025
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The transplantation of spinal allografts to correct defects that include disc, body, or segments of both is currently under experimental investigation. A method of graft preservation that will least compromise the biomechanical integrity of the bodies or discs is required. Using a five-mode biomechanical analysis, the authors compared the change in stiffness of ten preserved canine spines. The freeze-dried specimens lost a significantly greater amount of stiffness in compression, flexion, extension, and torsion than did the frozen specimens. Therefore, from a biomechanical viewpoint, deep-freezing is superior to freeze-drying for spinal allograft preservation. © Lippincott-Raven Publishers.
引用
收藏
页码:567 / 570
页数:4
相关论文
共 11 条
[1]
Bright R., Burchardt H., The Biomechanical Properties of Preserved Bone Grafts, Osteochondral Allografts: Biology, Banking and Clinical Applications, pp. 241-247, (1983)
[2]
Eyring E., The biochemistry and physiology of the intervertebral disk, Clin Orthop, 67, (1969)
[3]
Friedlaender G., Mankin H., Langer F., Immunology of Osteochondral Allografts: Background and General Considerations, Osteochondral Allografts: Biology, Banking and Clinical Applications, (1983)
[4]
Hickey D., Hukins D., Effect of methods of preservation on the arrangement of collagen fibrils in connective tissue matrices: An x-ray diffraction study of annulus fibrosus, Connect Tissue Res, 6, (1979)
[5]
Malinin T., Thomson C., Brown M., Freeze-Dried Tissue Allografts in Surgery, Organ Preservation for Transplantation, pp. 677-689, (1981)
[6]
Malinin T., Martinez O., Brown M., Banking of massive osteoarticular and intercalary bone grafts—12 years experience, Clin Orthop, 197, (1985)
[7]
Nachemson A., In vivo discometry in lumbar discs with irregular nucleo- grams, Acta Orthop Scand, 36, (1965)
[8]
Nachemson A., Electromyographic studies in the vertebral portion of the psoas muscle, Acta Orthop Scand, 37, (1966)
[9]
Pelker R., Friedlaender G., Markham T., Panjabi M., Moen C., Effects of freezing and freeze-drying on the biomechanical properties of rat bone, J Orthop Res, 1, pp. 405-410, (1984)
[10]
Perry V., Freeze-drying for the preservation of human tissues, Transplant Proc, 8, 2, (1976)