TOTALLY SYNTHETIC VOLTAGE-DEPENDENT ION-CHANNEL

被引:35
作者
KOBUKE, Y [1 ]
UEDA, K [1 ]
SOKABE, M [1 ]
机构
[1] NAGOYA UNIV,SCH MED,DEPT PHYSIOL,SHOWA KU,NAGOYA,AICHI 466,JAPAN
关键词
D O I
10.1246/cl.1995.435
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Phosphate monoester of tetra(butylene 1,4-glycol) monobutyl ether was combined with dioctadecyldimethylammonium cation to make an ion pair. When inserted into planar lipid bilayers, it afforded stable and constant single ion channel currents. The open probabilities varied depending on the applied voltage while keeping the conductance constant, giving rise to a mimic of the voltage dependence.
引用
收藏
页码:435 / 436
页数:2
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