METHOTREXATE OSTEOPATHY

被引：126

作者：

SCHWARTZ, AM ^{[1
]}

LEONIDAS, JC ^{[1
]}

机构：

[1] TUFTS UNIV, SCH MED, BOSTON, MA 02111 USA

来源：

SKELETAL RADIOLOGY | 1984年 / 11卷 / 01期

关键词：

D O I：

10.1007/BF00361126

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Methotrexate osteopathy is an uncommon complication of long-term oral maintenance therapy for childhood neoplasms, most commonly acute lymphocytic leukemia. I It is characterized by severe lower extremity pain and by osteoporosis particularly involving the lower extremities and thick dense provisional zones of calcification and growth arrest lines resembling scurvy. Fractures may occur. The appearance must be distinguished from recurrent or metastatic disease.

引用

页码：13 / 16

页数：4

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