METABOLISM OF THE NEUROTOXIC TERTIARY AMINE, MPTP, BY BRAIN MONOAMINE-OXIDASE

被引：1045

作者：

CHIBA, K ^{[1
]}

TREVOR, A ^{[1
]}

CASTAGNOLI, N ^{[1
]}

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT PHARMACEUT CHEM,SAN FRANCISCO,CA 94143

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1984年 / 120卷 / 02期

关键词：

D O I：

10.1016/0006-291X(84)91293-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：574 / 578

页数：5

共 15 条

[1]

ARRAIZ RD, 1967, J NEUROCHEM, V14, P215

[2] A PRIMATE MODEL OF PARKINSONISM - SELECTIVE DESTRUCTION OF DOPAMINERGIC-NEURONS IN THE PARS COMPACTA OF THE SUBSTANTIA NIGRA BY N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE [J].

BURNS, RS ;

CHIUEH, CC ;

MARKEY, SP ;

EBERT, MH ;

JACOBOWITZ, DM ;

KOPIN, IJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (14) :4546-4550

[3]

DEMAREST KT, 1980, J PHARMACOL EXP THER, V215, P461

[4]

GRAHAM DG, 1978, MOL PHARMACOL, V14, P644

[5]

HEIKKITA R, COMMUNICATION

[6]

LANG T, 1979, J MED CHEM, V22, P259

[7] CHRONIC PARKINSONISM IN HUMANS DUE TO A PRODUCT OF MEPERIDINE-ANALOG SYNTHESIS [J].

LANGSTON, JW ;

BALLARD, P ;

TETRUD, JW ;

IRWIN, I .

SCIENCE, 1983, 219 (4587) :979-980

[8]

LOWRY OH, 1951, J BIOL CHEM, V193, P265

[9]

MARIETTA MP, 1979, J PHARMACOL EXP THER, V208, P271

[10]

MARKEY SP, 1983, P ACNP SAN JUAN

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