TIME-RESOLVED LASER-INDUCED FLUORESCENCE SPECTROSCOPY FOR ENHANCED DEMARCATION OF HUMAN ATHEROSCLEROTIC PLAQUES

被引：22

作者：

ANDERSSONENGELS, S

JOHANSSON, J

STENRAM, U

SVANBERG, K

SVANBERG, S

机构：

[1] LUND INST TECHNOL,DEPT PHYS,POB 118,S-22100 LUND,SWEDEN

[2] UNIV LUND HOSP,DEPT PATHOL,S-22185 LUND,SWEDEN

[3] UNIV LUND HOSP,DEPT INTERNAL MED,S-22185 LUND,SWEDEN

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY | 1990年 / 4卷 / 04期

关键词：

Atherosclerosis; fluorescence; picosecond laser; time-resolved spectroscopy; tissue diagnosis;

D O I：

10.1016/1011-1344(90)85015-O

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We report on the enhanced demarcation between human atherosclerotic plaques and normal vessel wall obtained using time-resolved detection of laser-induced fluorescence rather than the customary time-integrated monitoring technique. A frequency-doubled mode-locked and cavity- dumped continuous wave dye laser was used for picosecond pulse generation at 320 nm, and photon-counting techniques were employed for the time- resolved signal monitoring from human aorta samples in vitro. Implications for imaging fluorescence angioscopy and spectroscopic guidance in laser ablation of plaque are indicated. © 1990.

引用

页码：363 / 369

页数：7

共 13 条

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