GATED TC-99M-MIBI MYOCARDIAL-FUNCTION IMAGING

被引：4

作者：

AVERY, PG

WILLIAMS, H

EARLY, MY

HUDSON, NM

HUBNER, PJB

机构：

[1] Regional Cardiothoracic Unit, Groby Road Hospital, Leicester, Groby Road

来源：

NUCLEAR MEDICINE COMMUNICATIONS | 1991年 / 12卷 / 08期

关键词：

D O I：

10.1097/00006231-199108000-00003

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The introduction of the Tc-99(m) isonitrile perfusion agents has provided improved myocardial image quality with conventional imaging equipment allowing improved edge definition on gating. We evaluated left ventricular wall motion in 46 patients using gated Tc-99(m)-2-methoxy-2-methyl-isopropyl-1-isonitrile (MIBI) scintigraphy. Using a method of myocardial profiles in four axes, global and regional fractional shortening (FS) were assessed. A good correlation was found between FS in the left anterior oblique (LAO) 40-degrees projection and ejection fraction (EF) on gated radionuclide ventriculography (r = 0.81, P < 0.001). This was improved by using FS in two planes, LAO 40-degrees and anterior (r = 0.88, P < 0.001). There was also a good correlation between FS in two planes and EF on cine-angiography (r = 0.72, P < 0.001). There was good intra- and interobserver agreement with the studies. Assessment of myocardial function using gated MIBI imaging and myocardial profiles provides useful additional information to the perfusion scan, thus enhancing the diagnostic usefulness of the agent.

引用

页码：677 / 685

页数：9

共 13 条

[1]

Zaret B.L., Strauss H.W., Martin N.D., Wells H.P., McGowan R.L., Flamm M.D., Non-invasive regional myocardial perfusion with radioactive potassium, N Engl J Med, 288, pp. 809-812, (1973)

[2]

Khalil M.N., Thornback J., Early M.Y., Morton D.B., Berry J.M., Hubner P., Technetium 99m isonitrile complex as a potential myocardial imaging agent, Nucl Med Commun, 6, pp. 615-622, (1985)

[3]

Najm Y.C., Maisey M.N., Fogelman I., Clarke S., Curry P., Sowton E., Exercise scintigraphy for coronary artery disease detection using new Tc-99m labelled myocardial imaging agent: Comparison with thallium-201, Nucl Med Commun, 8, (1987)

[4]

McKusick K., Holman B.L., Jones A.G., Et al., Comparison of three isonitriles for detection of ischaemic heart disease in humans, J Nucl Med, 878, (1986)

[5]

Mason D.T., Ashburn W.L., Harbert J.C., Rapid sequential visualization of the heart and great vessels in man using the wide field Anger scintillation camera, Circulation, 39, pp. 19-28, (1969)

[6]

Strauss H.W., Zaret B.L., Hurley P.J., Natarajan T.K., Pitt B., A scintiphotographic method for measuring left ventricular ejection fraction in man without cardiac catheterisation, Am J Cardiol, 28, pp. 575-580, (1971)

[7]

Zaret B.L., Strauss H.W., Hurley P.J., Natarajan T.K., Pitt B., A non-invasive scintiphotographic method for detecting regional ventricular dysfunction in man, N Engl J Med, 284, pp. 1165-1170, (1971)

[8]

Alderson P.O., Wagner H.N., Gomez-Moeiras J.J., Et al., Simultaneous detection of myocardial perfusion and wall motion abnormalities by cinematic 201T1 imaging, Radiology, 127, pp. 531-533, (1978)

[9]

Martin W., Tweddle A.C., McGhie A.I., Hutton I., Gated thallium scintigraphy in patients with coronary artery disease: An improved planar imaging technique, Clin Phys Physiol Meas, 8, pp. 343-354, (1987)

[10]

Mousa S.A., Cooney J.M., Williams S.J., Regional myocardial distribution of RP-30 in animal models of myocardial ischaemia and reperfusion, J Nucl Med, 620, (1987)

← 1 2 →