DRUG DETECTION IN HAIR BY CHROMATOGRAPHIC PROCEDURES

被引：53

作者：

MOELLER, MR

机构：

[1] Institut für Rechtsmedizin der Universität des Saarlandes

来源：

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1992年 / 580卷 / 1-2期

关键词：

D O I：

10.1016/0378-4347(92)80532-U

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

This article reviews the analysis of 31 drugs and drug metabolites in human hair by thin-layer chromatography, high-performance liquid chromatography, gas chromatography, gas chromatography-mass spectrometry and mass spectrometry. The most important detection method after chromatographic separation of the components is the mass spectrometry because of its sensitivity and specifity. Washing steps to exclude external contamination, extraction, derivatization, stationary phases, detection modes and detection limits of the mass spectrometric and gas chromatographic-mass spectrometric procedures are presented in five tables. Additionally, a method for a gas chromatographic-mass spectrometric screening procedure is presented.

引用

页码：125 / 134

页数：10

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