THE EFFECTS OF INBREEDING ON DNA PROFILE FREQUENCY ESTIMATES USING PCR-BASED LOCI

被引：6

作者：

BUDOWLE, B

机构：

[1] Forensic Science Research and Training Center, FBI Academy, Quantico, 22135, VA

来源：

GENETICA | 1995年 / 96卷 / 1-2期

关键词：

AFRICAN AMERICAN; CAUCASIAN; ORIENTAL; HISPANIC; INBREEDING; POPULATION SUBSTRUCTURE; PCR; HARDY-WEINBERG EXPECTATIONS; DNA PROFILE;

D O I：

10.1007/BF01441148

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Estimates of inbreeding were determined using Wright's F-ST for loci used for PCR-based forensic analyses. The populations analyzed were African Americans, Caucasians, Hispanics, and Orientals. In most cases the F-ST values at each locus were less than 0.01. The F-ST values over all loci for African Americans, Caucasians, and Orientals ranged from 0.0015 to 0.0048. No substantial differences were observed for DNA profile frequency estimates when calculated under the assumption of independence or with the incorporation of F-ST.

引用

页码：21 / 25

页数：5

共 36 条

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