AN IMMUNOELECTRON MICROSCOPIC STUDY OF THE EXPRESSION OF CLASS-II MAJOR HISTOCOMPATIBILITY COMPLEX DURING CHRONIC RELAPSING EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS IN BIOZZI AB/H MICE

被引：26

作者：

BUTTER, C ^{[1
]}

ONEILL, JK ^{[1
]}

BAKER, D ^{[1
]}

GSCHMEISSNER, SE ^{[1
]}

TURK, JL ^{[1
]}

机构：

[1] IMPERIAL CANC RES FUND,LONDON WC2A 3PZ,ENGLAND

来源：

JOURNAL OF NEUROIMMUNOLOGY | 1991年 / 33卷 / 01期

关键词：

CLASS-II MAJOR HISTOCOMPATIBILITY COMPLEX; EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS; IMMUNOELECTRON MICROSCOPY; (MOUSE);

D O I：

10.1016/0165-5728(91)90032-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Immunoelectron microscopical techniques have been used to study class II major histocompatibility complex (MHC) expression by cells in the spinal cords of Biozzi AB/H mice with chronic relapsing experimental allergic encephalomyelitis. Throughout the course of disease both astrocytes and endothelia failed to express significant levels of class II MHC antigens. The major central nervous system resident cell types found to express class II MHC antigens were the perivascular microglia, with infiltrating macrophages and some lymphocytes being strongly positive.

引用

页码：37 / 42

页数：6

共 18 条

[1] EFFECT OF ANTICANCER DRUGS ON THE RELEASE OF INTERFERON-GAMMA INVITRO [J].