INTESTINAL STENOSIS AND PERFORATING COMPLICATIONS IN CROHNS-DISEASE

被引：10

作者：

MAKOWIEC, F ^{[1
]}

JEHLE, EC ^{[1
]}

KOVEKER, G ^{[1
]}

BECKER, HD ^{[1
]}

STARLINGER, M ^{[1
]}

机构：

[1] UNIV TUBINGEN,DEPT GEN SURG,TUBINGEN,GERMANY

来源：

INTERNATIONAL JOURNAL OF COLORECTAL DISEASE | 1993年 / 8卷 / 04期

关键词：

D O I：

10.1007/BF00290305

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The charts of 384 patients with Crohn's disease were reviewed to assess the prognostic value of a bowel stenosis documented at the time of initial diagnosis for the occurrence of perforating (abscess, fistula, free perforation) or obstructing complications requiring surgical intervention. Mean follow-up was 5.6 years. At time of diagnosis a bowel stenosis (S) was documented in 143 patients (37.2%). 130 patients underwent surgery, 62 (48%) for obstruction, 18 (14%) for a perforating complication, 12 (9%) for both obstructing and perforating complication and 38 (29%) for intractable disease. The cumulative rates of surgery were calculated using lifetable analysis. The presence of a stenosis at the time of initial diagnosis was a risk factor for the likelihood of surgery overall [65% (S) vs. 40% (no S) after 10 years; P<0.001] and of surgery for obstruction [70% (S) vs. 34% (no S); P<0.001] but did not increase the likelihood of a perforating complication [24% (S) vs. 29% (no S); n.s.]. A perforating complication requiring surgery may therefore not be predicted by the mere diagnosis of a stenosis. Prophylactic surgery of stenotic lesions in patients with Crohn's disease to prevent the development of a perforating complication therefore is not recommended.

引用

页码：197 / 200

页数：4

共 10 条

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