Platelet interactions as therapeutic targets for prevention of atherothrombosis

被引：3

作者：

Smid, Jan ^{[2
]}

Braun-Dullaeus, Ruediger ^{[2
]}

Gawaz, Meinrad ^{[1
]}

Langer, Harald F. ^{[1
]}

机构：

[1] Eberhard Karls Univ Tuebingen, Kardiol, Med Klin 2, Otfried Muellerstr 10, D-72076 Tubingen, Germany

[2] Univ Klinikum Magdeburg, Univ Klin Kardiol Angiol & Pneumol, D-39120 Magdeburg, Germany

来源：

FUTURE CARDIOLOGY | 2009年 / 5卷 / 03期

关键词：

atherothrombosis; cell-cell interaction; inflammation; platelet; therapy;

D O I：

10.2217/FCA.09.9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Physiologically, platelets perform important tasks to maintain the homeostasis of the vascular wall and the surrounding environment. In pathologic conditions, however, platelets contribute to the formation of atherosclerotic plaques as well as to atherothrombotic events (i.e., acute myocardial infarction). This review aims to elucidate the role of platelets in atherogenesis and atherothrombosis and to provide an insight into current and future strategies for platelet inhibition.

引用

页码：285 / 296

页数：12

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