D-PENICILLAMINE FOR TREATMENT OF GOLD DERMATITIS

D-penicillamine was effective in the treatment of a case of persistent gold dermatitis. Clinical improvement occurred after the administration of 1 gm. of penicillamine daily for seven days. Increased urinary gold excretion, fecal gold excretion and plasma gold levels were demonstrated by neutron activation analysis. Although d-penicillamine is effective in the treatment of gold toxicity, its use should be reserved for chronic toxicity which has not responded to more conservative methods. © 1969.