DIASTEREOSELECTIVE ADDITION OF ALPHA-SULFINYL ESTER ENOLATE WITH BENZALDIMINES POSSESSING AN ELECTRON-WITHDRAWING GROUP AT THE NITROGEN ATOM

被引：10

作者：

SHIMIZU, M ^{[1
]}

KOORIYAMA, Y ^{[1
]}

FUJISAWA, T ^{[1
]}

机构：

[1] MIE UNIV, DEPT CHEM MAT, TSU, MIE 514, JAPAN

来源：

CHEMISTRY LETTERS | 1994年 / 12期

关键词：

D O I：

10.1246/cl.1994.2419

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction of optically pure alpha-sulfinyl ester enolate with benzaldimines possessing an electron withdrawing group at the nitrogen atom gave beta-amino ester in both enantiomeric forms in satisfactory optical and chemical yields (up to 94%ee), in which the changeover of the diastereofacial selectivity was induced by suitable choice of the protecting group at the nitrogen and the use of additives.

引用

页码：2419 / 2422

页数：4

共 26 条

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