UNBALANCED 6P TRANSLOCATION AS PRIMARY KARYOTYPIC ANOMALY IN SECONDARY ACUTE NONLYMPHOCYTIC LEUKEMIA

被引：4

作者：

MANCINI, M ^{[1
]}

MECUCCI, C ^{[1
]}

CEDRONE, M ^{[1
]}

RONDINELLI, MB ^{[1
]}

ALOESPIRITI, MA ^{[1
]}

ALIMENA, G ^{[1
]}

机构：

[1] UNIV PERUGIA,INST HEMATOL,I-06100 PERUGIA,ITALY

来源：

CANCER GENETICS AND CYTOGENETICS | 1992年 / 60卷 / 01期

关键词：

D O I：

10.1016/0165-4608(92)90242-Z

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A case of acute nonlymphocytic leukemia after radiochemotherapy for Hodgkin's disease, with a rearrangement of 6p23 region, is described. This chromosome change, which has been previously reported in secondary leukemias or myelodysplastic syndromes, was an isolated karyotypic anomaly in our case, which strongly supports the nonrandom involvement of chromosome 6p in induced leukemias.

引用

页码：93 / 95

页数：3

共 10 条

[1]

HARDEN DG, 1985, BIRTH DEFECTS ORIGIN, V21

[2]

HARDEN DG, 1985, CANCER GENET CYTOGEN

[3] CHROMOSOME-6P REARRANGEMENTS APPEAR TO BE SECONDARY CHANGES IN VARIOUS HEMATOLOGICAL MALIGNANCIES [J].