STERNAL OSTEOMYELITIS DUE TO ASPERGILLUS-FUMIGATUS AFTER CARDIAC-SURGERY

被引:18
作者
BARZAGHI, N [1 ]
EMMI, V [1 ]
MENCHERINI, S [1 ]
MINZIONI, G [1 ]
MARONE, P [1 ]
MINOLI, L [1 ]
机构
[1] UNIV PAVIA,POLICLIN SAN MATTEO,INFECT DIS CLIN,I-27100 PAVIA,ITALY
关键词
D O I
10.1378/chest.105.4.1275
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Sternal osteomyelitis due to Aspergillus fumigatus after cardiac surgery occurred in two nonimmunosuppressed patients. The clinical features of the infection were markedly different in the two cases. In the first patient, sepsis showed a late and insidious onset followed by slow progression. In the second case, fungi were isolated from wound swabs within a few days of surgery and the clinical picture showed acute onset and rapid progression. Only a fe rv cases of sternal osteomyelitis due to Aspergillus have been described previously after cardiac surgery. Aspergillus infection should be considered in the differential diagnosis of mediastinitis after cardiac surgery, especially in a clinical setting of otherwise unexplained sepsis or nonhealing wound despite apparently adequate treatment.
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收藏
页码:1275 / 1277
页数:3
相关论文
共 12 条
  • [1] GRANULOMATOUS MEDIASTINITIS DUE TO ASPERGILLUS-FLAVUS IN A NON-IMMUNOSUPPRESSED PATIENT
    AHMAD, M
    WEINSTEIN, AJ
    HUGHES, JA
    COSGROVE, DE
    [J]. AMERICAN JOURNAL OF MEDICINE, 1981, 70 (04) : 887 - 890
  • [2] ATTAH CA, 1979, NEW YORK STATE J MED, V79, P1420
  • [3] Bennett J. E., 1990, Principles and practice of infectious diseases., P1958
  • [4] DENNING DW, 1990, REV INFECT DIS, V12, P1147
  • [5] FROMTILING R A, 1988, Clinical Microbiology Reviews, V1, P187
  • [6] IMMUNODIAGNOSIS OF ASPERGILLOSIS
    KURUP, VP
    KUMAR, A
    [J]. CLINICAL MICROBIOLOGY REVIEWS, 1991, 4 (04) : 439 - 456
  • [7] Levitz S M, 1989, Infect Dis Clin North Am, V3, P1
  • [8] MUSIAL C E, 1988, Clinical Microbiology Reviews, V1, P349
  • [9] AMPHOTERICIN-RESISTANT ASPERGILLUS OSTEOMYELITIS CONTROLLED BY ITRACONAZOLE
    SACHS, MK
    PALUZZI, RG
    MOORE, JH
    FRAIMOW, HS
    OST, D
    [J]. LANCET, 1990, 335 (8703) : 1475 - 1475
  • [10] SARAL R, 1991, REV INFECT DIS, V13, P487