CLONING AND SEQUENCING OF A CDNA-ENCODING A NOVEL MEMBER OF THE HUMAN BRAIN GABA/NORADRENALINE NEUROTRANSMITTER TRANSPORTER FAMILY

被引:12
作者
BARNWELL, LFS
CHAUDHURI, G
TOWNSEL, JG
机构
[1] MEHARRY MED COLL,DEPT PHYSIOL,NASHVILLE,TN 37208
[2] MEHARRY MED COLL,DIV BIOMED SCI,NASHVILLE,TN 37208
关键词
CODING SEQUENCE; CREATINE TRANSPORTER; CHOLINE TRANSPORTER;
D O I
10.1016/0378-1119(95)00104-E
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Screening of a human hippocampal cDNA library with a rat creatine transporter cDNA-specific probe revealed two types of clones, One identical to the published creatine transporter cDNA sequence (CRT1) and another (CRT2) with four segments of oligodeoxyribonucleotide substitution or addition in different sites of the CRT1 coding sequence, Translation of the CRT2 coding sequence reveals a new protein with regions of perfect homology with the CRT1 amino-acid sequence.
引用
收藏
页码:287 / 288
页数:2
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