RAPID EMERGENCE OF QUINOLONE RESISTANCE IN CAMPYLOBACTER-JEJUNI IN PATIENTS TREATED WITH NORFLOXACIN

被引：25

作者：

WRETLIND, B

STROMBERG, A

OSTLUND, L

SJOGREN, E

KAIJSER, B

机构：

[1] DANDERYD HOSP,DEPT INFECT DIS,S-18288 DANDERYD,SWEDEN

[2] GOTHENBURG UNIV,DEPT CLIN BACTERIOL,S-41124 GOTHENBURG,SWEDEN

来源：

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES | 1992年 / 24卷 / 05期

关键词：

D O I：

10.3109/00365549209054659

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

15/60 subjects from one center, who all took part in a multicenter double-blind, placebo-controlled study to evaluate the effect of norfloxacin on acute enteritis, had norfloxacin sensitive strains of Campylobacter jejuni in pre-study stool specimens. Eight of the 15 subjects received active drug. In 3 of these 8, high-level quinolone resistant Campylobacter strains of the same serotype as in pre-treatment samples were isolated 4-90 days after the initiation of treatment.

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页码：685 / 686

页数：2

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