INTERFERON-GAMMA - A KEY IMMUNOREGULATORY LYMPHOKINE

被引：75

作者：

WILLIAMS, JG

JURKOVICH, GJ

MAIER, RV

机构：

[1] Department of Surgery, University of Washington School of Medicine, Harborview Medical Center, Seattle

来源：

JOURNAL OF SURGICAL RESEARCH | 1993年 / 54卷 / 01期

关键词：

D O I：

10.1006/jsre.1993.1013

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Interferon-γ is an important component of numerous host responses to inflammatory insults. Data from in vitro and animal studies suggest that this agent may have clinical uses in immunocompromised patients who are at increased risk for infectious complications. In addition to reviewing our current understanding of the in vitro and in vivo actions of interferon-γ, this article cautions that the potential for adverse reactions exists when interferon-γ is administered to an immunologically competent host. © 1993 Academic Press. All rights reserved.

引用

页码：79 / 93

页数：15

共 150 条

[1] MOLECULAR TRANSDUCTIONAL MECHANISMS BY WHICH IFN-GAMMA AND OTHER SIGNALS REGULATE MACROPHAGE DEVELOPMENT [J].