ASYMMETRIC-SYNTHESIS .21. THE 1ST ENANTIOSELECTIVE SYNTHESIS OF NATURAL (+)-TETRAPONERINE-8 - A NEW EXTENTION OF THE CN(R,S) METHOD TO AN UNCOMMON SKELETON

被引：40

作者：

YUE, CW ^{[1
]}

ROYER, J ^{[1
]}

HUSSON, HP ^{[1
]}

机构：

[1] CNRS,INST CHIM SUBST NAT,F-91198 GIF SUR YVETTE,FRANCE

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 04期

关键词：

D O I：

10.1021/jo00291a007

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first synthesis of natural (+)-tetraponerine-8 (1) has been accomplished in six steps and 34% overall yield from 2-cyano-6-oxazolopiperidine synthon 5 and has allowed assignment of the absolute configuration. © 1990, American Chemical Society. All rights reserved.

引用

页码：1140 / 1141

页数：2

共 9 条

[1]

Ban Y, 1974, HETEROCYCLES, V2, P323

[2]

BRAEKMAN JC, 1987, Z NATURFORSCH C, V42, P627

[3] CHIRAL 1,4-DIHYDROPYRIDINE EQUIVALENTS - A NEW APPROACH TO THE ASYMMETRIC-SYNTHESIS OF ALKALOIDS - THE ENANTIOSPECIFIC SYNTHESIS OF (+)-CONIINE AND (-)-CONIINE AND DIHYDROPINIDINE [J].