USE OF ANTIBIOTICS IN LIVESTOCK AND HUMAN HEALTH CONCERNS

被引:23
作者
GUSTAFSON, RH
机构
[1] American Cyanamid Co., Agricultural Research Division, Princeton, New Jersey
关键词
ANTIBIOTIC RESIDUES; ANTIBIOTIC RESISTANCE; FEED ADDITIVES;
D O I
10.3168/jds.S0022-0302(91)78299-4
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
Animal feed additives have for many years constituted the largest and most controversial category of antimicrobial use. The primary concerns addressed have been the generation of antibiotic resistance in animal bacteria and the influence of such resistance on human health. Studies designed to shed light on the controversy generally have yielded information leading to ambiguous conclusions. A 1989 report from the National Academy of Sciences was the latest of a long collection of assessments that have been meant to provide expert guidance to regulatory authorities on this matter. The FDA has been trying for some time to determine whether a regulatory decision on existing products is warranted. After several decades of research directed at this question, most qualified study groups have reported a paucity of appropriate information necessary to judge the reality of a public health risk.
引用
收藏
页码:1428 / 1432
页数:5
相关论文
共 13 条
[1]   ANTIMICROBIAL AGENT SUSCEPTIBILITY PATTERNS OF BACTERIA IN HOSPITALS FROM 1971 TO 1982 [J].
ATKINSON, BA ;
LORIAN, V .
JOURNAL OF CLINICAL MICROBIOLOGY, 1984, 20 (04) :791-796
[2]   ANIMAL-TO-MAN TRANSMISSION OF ANTIMICROBIAL-RESISTANT SALMONELLA - INVESTIGATIONS OF UNITED-STATES OUTBREAKS, 1971-1983 [J].
HOLMBERG, SD ;
WELLS, JG ;
COHEN, ML .
SCIENCE, 1984, 225 (4664) :833-835
[3]   DRUG-RESISTANT SALMONELLA FROM ANIMALS FED ANTIMICROBIALS [J].
HOLMBERG, SD ;
OSTERHOLM, MT ;
SENGER, KA ;
COHEN, ML .
NEW ENGLAND JOURNAL OF MEDICINE, 1984, 311 (10) :617-622
[4]  
LANGLOIS B E, 1986, J ANIM SCI S3, V62, P18
[5]   ANTIBIOTIC-RESISTANCE OF FECAL COLIFORMS FROM SWINE FED SUBTHERAPEUTIC AND THERAPEUTIC LEVELS OF CHLORTETRACYCLINE [J].
LANGLOIS, BE ;
DAWSON, KA ;
STAHLY, TS ;
CROMWELL, GL .
JOURNAL OF ANIMAL SCIENCE, 1984, 58 (03) :666-674
[6]   SALMONELLA SUSCEPTIBILITY PATTERNS IN HOSPITALS FROM 1975 THROUGH 1984 [J].
LORIAN, V .
JOURNAL OF CLINICAL MICROBIOLOGY, 1986, 23 (05) :826-827
[7]  
NETHERTHORPE, 1962, AGR RES COUNC MED RE
[8]  
OBRIEN TF, 1987, REV INFECT DIS, V9, pS244
[9]  
SIKA JS, 1987, NEW ENGL J MED, V316, P565
[10]  
Swann MM, 1969, JOINT COMMITTEE USE