QUANTITATIVE-ANALYSIS OF FLUOROQUINOLONES BY H-1-NMR AND F-19-NMR SPECTROSCOPY

被引：28

作者：

FARDELLA, G

BARBETTI, P

CHIAPPINI, I

GRANDOLINI, G

机构：

[1] Institute of Pharmaceutical Chemistry and Technology, University of Perugia, Perugia

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1995年 / 121卷 / 01期

关键词：

ANTIBIOTIC; FLUOROQUINOLONE; PEFLOXACIN; NORFLOXACIN; OFLOXACIN; QUANTIFICATION; H-1-NMR; F-19-NMR;

D O I：

10.1016/0378-5173(95)00038-K

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

H-1- and F-19-NMR assay of pefloxacin (I), norfloxacin (II) and ofloxacin (III) in some pharmaceutical forms has been developed. The method, based on the integration of appropriate signals of both analytes and internal standards, is simple, rapid, precise, and accurate, and can be used for quality control of these drugs.

引用

页码：123 / 127

页数：5

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[2]

CHENON MT, 1990, ANALYSIS, V18, P151

[3]

DEROME AE, 1988, ORGANIC CHEM SERIES, V6, P86

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