ENVELOPE GENE SEQUENCE OF HTLV-1 ISOLATE MT-2 AND ITS COMPARISON WITH OTHER HTLV-1 ISOLATES

被引：82

作者：

GRAY, GS

WHITE, M

BARTMAN, T

MANN, D

机构：

[1] Repligen Corporation, Cambridge, MA 02139, One Kendall Square

来源：

VIROLOGY | 1990年 / 177卷 / 01期

关键词：

D O I：

10.1016/0042-6822(90)90498-G

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The DNA sequence of the envelope gene of the HTLV-1 proviral clone MT-2 was determined and compared with envelope sequences of other HTLV-1 isolates. The comparison of this sequence with another of Japanese origin and two of Caribbean origin does not support the proposal by K. T. A. Malik, J. Even, and A. Karpas (J. Gen. Virol. 69,1695-1710, 1988) that isolates of similar geographic origins are more homologous than isolates of different origins. No significant differences in the degree of homology could be found among the HTLV-1 envelope gene sequences from Japanese and Caribbean isolates. The comparison confirms the high degree of homology previously found between various HTLV-1 isolates (>97%). © 1990.

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页码：391 / 395

页数：5

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