MOLECULAR MECHANISMS OF RECEPTOR DESENSITIZATION USING THE BETA-ADRENERGIC RECEPTOR-COUPLED ADENYLATE-CYCLASE SYSTEM AS A MODEL

被引：821

作者：

SIBLEY, DR ^{[1
]}

LEFKOWITZ, RJ ^{[1
]}

机构：

[1] DUKE UNIV,MED CTR,DEPT BIOCHEM,DURHAM,NC 27710

来源：

NATURE | 1985年 / 317卷 / 6033期

关键词：

D O I：

10.1038/317124a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：124 / 129

页数：6

共 96 条

[1]

ANDERSON WB, 1979, J BIOL CHEM, V254, P4596

[2] BETA-ADRENERGIC REGULATION OF SERTOLI-CELL ADENYLYL CYCLASE - DESENSITIZATION BY HOMOLOGOUS HORMONE [J].

ATTRAMADAL, H ;

LEGAC, F ;

JAHNSEN, T ;

HANSSON, V .

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1984, 34 (01) :1-6

[3]

BAROVSKY K, 1983, J CYCLIC NUCL PROT, V9, P181

[4] THE MAMMALIAN BETA-2-ADRENERGIC RECEPTOR - PURIFICATION AND CHARACTERIZATION [J].

BENOVIC, JL ;

SHORR, RGL ;

CARON, MG ;

LEFKOWITZ, RJ .

BIOCHEMISTRY, 1984, 23 (20) :4510-4518

[5]

BENOVIC JL, 1985, J BIOL CHEM, V260, P7094

[6] FUNCTIONAL MODIFICATION OF THE GUANINE-NUCLEOTIDE REGULATORY PROTEIN AFTER DESENSITIZATION OF TURKEY ERYTHROCYTES BY CATECHOLAMINES [J].

BRIGGS, MM ;

STADEL, JM ;

IYENGAR, R ;

LEFKOWITZ, RJ .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1983, 224 (01) :142-151

[7]

CHUANG DM, 1980, MOL PHARMACOL, V18, P348

[8] BETA-ADRENERGIC RECEPTORS OF FROG ERYTHROCYTES - BIOCHEMICAL SEQUELAE FOLLOWING STIMULATION WITH ISOPROTERENOL [J].

CHUANG, DM ;

COSTA, E .

NEUROCHEMICAL RESEARCH, 1979, 4 (06) :777-793

[9] EVIDENCE FOR INTERNALIZATION OF THE RECOGNITION SITE OF BETA-ADRENERGIC RECEPTORS DURING RECEPTOR SUBSENSITIVITY INDUCED BY (-)-ISOPROTERENOL [J].

CHUANG, DM ;

COSTA, E .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1979, 76 (06) :3024-3028

[10]

CLARK RB, 1985, J CYCLIC NUCL PROT, V10, P97

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