HIGHLY STEREOSELECTIVE ACETYLATIONS VIA NOREPHEDRINE DERIVED OXAZOLIDINES

被引：9

作者：

BERNARDI, A ^{[1
]}

CAVICCHIOLI, M ^{[1
]}

POLI, G ^{[1
]}

SCOLASTICO, C ^{[1
]}

SIDJIMOV, A ^{[1
]}

机构：

[1] UNIV MILAN,CNR,CTR STUDIO SOSTANZE ORGAN,DIPARTIMENTO CHIM ORGAN & IND,I-20133 MILAN,ITALY

来源：

TETRAHEDRON | 1991年 / 47卷 / 37期

关键词：

ACETYLATION; STEREOSELECTIVE; EPHEDRINE; OXAZOLIDINE; SILYLENOLETHERS;

D O I：

10.1016/S0040-4020(01)81947-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Norephedrine derived 2-methoxy-2-methyl oxazolidine 2 is an efficient stereoselective acetylating agent in reactions with stereogenic silylenolethers and silylketenethiolacetals. Moderate selectivity is also obtained upon acetylation of crotyltin reagents. The present methodology compares favorably with the previously reported enantioselective Claisen-type acylations.

引用

页码：7925 / 7936

页数：12

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