POPULATION-DATA ON ACUTE INFANTILE AND CHRONIC CHILDHOOD SPINAL MUSCULAR-ATROPHY IN WARSAW

被引：26

作者：

SPIEGLER, AWJ

HAUSMANOWAPETRUSEWICZ, I

BORKOWSKA, J

KLOPOCKA, A

机构：

[1] MED ACAD WARSAW,DEPT NEUROL,PL-02032 WARSAW,POLAND

[2] POLISH ACAD SCI,NEUROMUSCULAR UNIT,WARSAW 42,POLAND

来源：

HUMAN GENETICS | 1990年 / 85卷 / 02期

关键词：

D O I：

10.1007/BF00193198

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

This study provides epidemiological data on acute infantile (ASMA) and chronic childhood spinal (CSMA) muscular atrophy in Warsaw for the period 1976-1985. All calculations are based on the assumption that ASMA and CSMA result from mutations at two different gene loci. The incidence of ASMA and CSMA was 1 in 19474 live births with a corresponding gene and carrier frequency of 714 × 10-5 and 1 in 70, respectively. The prevalance of CSMA for the year 1985 was 1.26 × 10-5. These figures are higher than in similar studies in other countries. This fact might be connected with the careful ascertainment in this study. © 1990 Springer-Verlag.

引用

页码：211 / 214

页数：4

共 24 条

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[2]

BOUWSMA G, 1986, CLIN GENET, V30, P145

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