MOLECULAR MARKER ANALYSIS OF SALMONELLA-TYPHIMURIUM FROM SURFACE WATERS, HUMANS, AND ANIMALS

被引：12

作者：

GRAEBER, I ^{[1
]}

MONTENEGRO, MA ^{[1
]}

BUNGE, C ^{[1
]}

BOETTCHER, U ^{[1
]}

TOBIAS, H ^{[1
]}

HEINEMEYER, EA ^{[1
]}

HELMUTH, R ^{[1
]}

机构：

[1] BUNDESINST GESUNDHEITLICHEN VERBRAUCHERSCHUTZ & V,D-12277 BERLIN,GERMANY

来源：

EUROPEAN JOURNAL OF EPIDEMIOLOGY | 1995年 / 11卷 / 03期

关键词：

MULTI-RESISTANCE; PLASMID TYPING; PHAGE TYPE 204C; SALMONELLA TYPHIMURIUM; SEWAGE;

D O I：

10.1007/BF01719438

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Salmonella contamination of North Sea water was detected for the first time in 1988 in Germany during routine examinations of bathing areas. Since then, subsequent isolations along the coast have been reported regularly. To define the source of contamination, strains isolated from seawater and rivers were studied by molecular marker methods. Their properties were compared with those of strains originating from possible sources of contamination such as humans, cattle, and sewage treatment plant water. Plasmid profile analysis of whole bacterial populations and the determination of antibiotic resistance patterns demonstrated, that contamination through the surrounding cattle industry could be excluded. Cattle isolates belonged to a widespread clone of phage type 204c which was multiresistant and exhibited an unique plasmid pattern which was never found in sea water isolates. Outer membrane protein and lipopolysaccharide analysis failed to demonstrate differences among the Salmonella populations and proved in this case insufficient for molecular marker discrimination.

引用

页码：325 / 331

页数：7

共 39 条

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