OXIDATION OF METHYL P-TOLYL SULFIDE WITH BAKERS-YEAST - PREPARATION OF A SYNTHON OF THE MEVINIC ACID-TYPE HYPOCHOLESTEMIC AGENTS

被引：23

作者：

BEECHER, J

BRACKENRIDGE, I

ROBERTS, SM

TANG, J

WILLETTS, AJ

机构：

[1] UNIV EXETER,DEPT CHEM,EXETER EX4 4QD,DEVON,ENGLAND

[2] UNIV EXETER,DEPT SCI BIOL,EXETER EX4 4QD,DEVON,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1995年 / 13期

关键词：

D O I：

10.1039/p19950001641

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Bakers' yeast oxidized methyl p-tolyl sulfide to produce the R-sulfoxide 1 in good yield and high enantiomeric excess; the sulfoxide 1 was used to prepare(4R,6S)- tert-butyldimethylsilyloxy-6-hydroxy-methyltetrahydropyran-2-one 15.

引用

页码：1641 / 1643

页数：3

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