TRICYCLIC ANTIDEPRESSANTS AND NEUROLEPTICS .4. STEREOSPECIFITY OF NEUROLEPTIC ACTIVITY AND CHIRALITY OF (+)-3-(2-[4-(8-FLUORO-2-METHYL-10, 11-DIHYDRODIBENZO[B,F]THIEPIN-10-YL)-1-PIPERAZINYL]ETHYL)-2-OXAZOLIDINONE (16)

被引：14

作者：

ASCHWANDEN, W ^{[1
]}

KYBURZ, E ^{[1
]}

SCHONHOLZER, P ^{[1
]}

机构：

[1] F HOFFMANN LA ROCHE & CO AG, CHEM & PHYS FORSCH ABT, BASEL, SWITZERLAND

来源：

HELVETICA CHIMICA ACTA | 1976年 / 59卷 / 04期

关键词：

D O I：

10.1002/hlca.19760590428

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis and stereospecific neuroleptic action in animals of the (+)-enantiomer of 3-{2-[4-(8-fluoro-2-methyl-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-1-piperazinyl[ethyl}-2-oxazolidinone are briefly described. The (10S)-configuration of this compound was determined by X-ray diffraction.

引用

页码：1245 / 1252

页数：8

共 17 条

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