PHOTOCATALYZED ADDITION OF ALCOHOLS TO 5-SUBSTITUTED 2,5-DIHYDROFURAN-2-ONES - NOVEL SYNTHESIS OF (3'R)-2',3'-DIDEOXY-3'-HYDROXYMETHYL NUCLEOSIDES

被引：33

作者：

MANN, J

WEYMOUTHWILSON, AC

机构：

[1] Department of Chemistry, Reading University, Reading RG6 2AD, Whiteknights

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1994年 / 21期

关键词：

D O I：

10.1039/p19940003141

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Methanol and propan-2-ol add in a regiospecific and highly stereocontrolled fashion to 5-substituted 2.5-dihydrofuran-2-ones (butenolides) under irradiation. The photoadducts with methanol have been converted into a number of (3'R)-2',3'-dideoxy-3'-hydroxymethyl nucleosides.

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页码：3141 / 3148

页数：8

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