CHROMOSOME ABNORMALITY IN RAT LEUKEMIA INDUCED BY 7,12-DIMETHYLBENZ[A]ANTHRACENE

被引：65

作者：

SUGIYAMA, T

KURITA, Y

NISHIZUKA, Y

机构：

来源：

SCIENCE | 1967年 / 158卷 / 3804期

关键词：

D O I：

10.1126/science.158.3804.1058

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A high percentage of consistent chromosome abnormality, tri-somy of the longest telocentric chromosome, was found in leukemias induced in rats of the Long-Evans strain by pulse doses of 7,12-di-methylbenz[a]anthracene. Cells with this abnormality were large, immature, and mononuclear and tended toward erythroblastic maturation.

引用

页码：1058 / +

页数：1

共 12 条

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[5] INDUCTION OF LEUKEMIA IN RAT BY PULSE DOSES OF 7,12-DIMETHYLBENZ(A)ANTHRACENE
HUGGINS, CB
SUGIYAMA, T
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1966, 55 (01) : 74 - &
[6] NOWELL PC, 1961, JNCI-J NATL CANCER I, V27, P1013
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[9] NOWELL PC, 1963, JNCI-J NATL CANCER I, V30, P687
[10] STICH HF, 1960, JNCI-J NATL CANCER I, V25, P649

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